Papers Presented, Conferences, Workshops

State of the art of mathematical models of cancer. Keynote Address. Lorentz Center Workshop: Understanding Cancer Through Evolutionary Game Theory. Leiden, NL. January 29, 2018.

[The following 4 talks are variations of the same material.]

A model of natural selection predicts treatment resistance in prostate cancer. ISEEC: International Society for Ecology, Evolution and Cancer Meetings. Tempe, AZ. December 8, 2017.

A model of natural selection predicts treatment resistance in prostate cancer. ICMA VI: Sixth International Conference on Mathematical Modeling and Analysis of Populations in Biological Systems. University of Arizona, Tucson. October 21, 2017.

A model of natural selection predicts treatment resistance in prostate cancer. Invited talk. Seminar in Applied Mathematics, Department of Mathematics and Statistics, Texas Tech University. Lubbock, TX. October 5, 2017.

A model of natural selection predicts treatment resistance in prostate cancer. Contributed talk. Society for Mathematical Biology Annual Meeting. Salt Lake City, UT. July 19, 2017.

An evolutionary model of androgen independence in advanced prostate cancer. (NOTE: an update of the previous talk.) Minisymposium: The Games That Cancer Cells Play. Organized by David Basanta. 10th ECMTB and SMB Annual Meeting. Nottingham, UK. July 14, 2016.

Tumor evolutionary ecology: Evolution of androgen independence in advanced prostate cancer. Special Session: Models for Treatment of Prostate Cancer. Organized by F. Milner and Y. Kuang. 11th AIMS Conference on Dynamical Systems, Differential Equations and Applications. Orlando, FL. June 1, 2016.

Tumor evolutionary ecology: Predicting the evolution of malignancy using resource ratio theory. Game Theory and Evolutionary Biology: Exploring Novel Links Workshop. Organized by J.A.J. Metz, N. Mideo, K. Stankova and F. Thuijsman. Lorentz Center, Leiden, Netherlands. April 21, 2016.

The inevitable partial collapse of an American pika metapopulation. Lead author and presenter: Easton White. Ecological Society of America Annual Meeting, Baltimore MD. August 13, 2015.

Coevolution of cancer hallmarks. Evolutionary Game Theory Workshop. Organized by Vlastimil Krivan, Andrew Belmonte, John Nagy and Zhijun Wu. Mathematical Biosciences Institute, Ohio State University, Columbus, OH. April 30, 2015.

Nothing in cancer biology makes sense except in the light of evolution (not even angiogenesis). Invited lecture in the Department of Mathematics and Statistics and TUCS Biohealth Program, University of Turku, Turku, Finland. March 3, 2015. (Note: a significant revision from the talk in Helsinki under the same title.)

Nothing in cancer biology makes sense except in the light of evolution (Parts 1 and 2). Invited talk in the Biomathematics Seminar of the Biomathematics Group, Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland. February 25, 2015.

Cancer evades evolutionary suicide by genetic hitchhiking. Biomathematics Day, Fall 2014. Organized by Mats Gyllenberg and Eva Kisdi. Finnish Centre of Excellence in Analysis and Dynamics Research, University of Helsinki. Helsinki, Finland. October 22, 2014.

The creative roles of selection and drift in the angiogenic switch in cancer. Workshop 1: Ecology and Evolution of Cancer. Mathematical Biosciences Institute, Ohio State University, Columbus OH. September 18, 2014.

Evolutionary suicide in cancer. Invited talk at the Physical Sciences Oncology Center/Department of Integrative Mathematical Oncology seminar. H. Lee Moffitt Cancer Center and Research Institute, Tampa FL. May 22, 2014.

The MCTP program at ASU and SCC, part 3: One week of mathematical biology. Copresenters: Eric Kostelich and Roberto Ribas. Ariz MATYC Meeting. Phoenix College.  Phoenix AZ. April 14, 2014.

Participant. Centers for Excellence in Genomic Sciences (NHGRI, NIH), 11th annual grantee meeting. University of Wisconsin, Madison. October 15-17, 2013.

Participant. National Human Genome Research Institute (NIH) Annual Meeting with DAP and T32 Grantees. University of Wisconsin, Madison. October 14 and 15, 2013.

The evolutionary ecology of cancer: Does natural selection drive androgen resistance in prostate cancer? Symposium: Where is the fruit? Successful collaborations between mathematicians and biologists. [Organized by Fabio Milner and Karen Rios-Soto.] 2013 SACNAS Conference. San Antonio, TX. October 5, 2013.

What ultimately causes androgen resistance in prostate cancer? Hypothesis-based, data-validated mathematical models of cancer minisymposium. [Organized by John Nagy and Yang Kuang.] 2013 Society for Mathematical Biology Annual Meeting. Tempe, AZ. June 10-13, 2013.

An evolutionary model of androgen-receptor expression in prostate cancer. Mathematical Modeling of Prostate Cancer Minisymposium. [Organized by Yoshito Hirata, Yang Kuang and Kazuyuki Aihara.] 2013 SIAM Conference on Applications of Dynamical Systems. Snowbird, UT. May 19-23, 2013.

The evolution of androgen receptor expression in prostate cancer. Biomathematics Day, Spring 2013. Organized by Mats Gyllenberg and Eva Kisdi. Finnish Centre of Excellence in Analysis and Dynamics Research, University of Helsinki. Helsinki, Finland. May 15, 2013.

Evolution of proliferation and the angiogenic switch in phenotypically diverse tumors. Invited talk at the TUCS Biomedicine program, University of Turku. [Coauthors: Scott Bickel and Joe Juliano.] Turku, Finland. May 14, 2013.

Evolutionary dynamics of dispersal in metapopulations of the American pika (Ochotona princeps).  46th Joint Annual Meeting of the AZ/NM Chapters of the Wildlife and American Fisheries Society. Albuquerque, NM. February 7-9, 2013.

Evolution of uncontrolled proliferation and the angiogenic switch in cancer. Mathematical Models in Biology and Medicine Symposium. [Organized by Yang Kuang, Bingtuan Li, Jiaxu Li and A. Nevai.] 9th AIMS Conference on Dynamical Systems, Differential Equations and Applications. Orlando, FL. July 1-5, 2012.

Long-Term Dynamics of an American Pika Metapopulation—Resilience at the Population and Individual Levels. Coauthor and presenter: Andrew T. Smith. Pikas in Peril? Distribution, Population Trends and Resilience of the American Pika (Ochotona princeps) Symposium. Society for Conservation Biology, North American Congress for Conservation Biology Meeting. Oakland, CA. July 15-18, 2012.

The evolution of dispersal in low-elevation populations of American pikas (Ochotona princeps) in the Great Basin, U.S.A. Modeling of Ecological Systems minisymposium. [Organized by Yun Kang (ASU), Yang Kuang (ASU) and Hao Wang (University of Alberta).] International Conference on Industrial and Applied Mathematics 2011. Vancouver, B.C., Canada. July 18-22, 2011.

Participant, Cancer as a Dynamical System Workshop. Discussion Leader: Angiogenesis as adaptive cooperation. Physical Sciences Oncology Center and Beyond Center for Fundamental Concepts in Science. Tempe, AZ. June 2-4, 2010.

Participant, 79th Annual Meeting of the Association of Physical Anthropologists. Albuquerque, NM. April 14-17, 2010.

Bodie Pikas: What They Have to Tell Us. Coauthors: Andrew T. Smith, Lyle B. Nichols and John D. Nagy. Presenter: Justine Smith. 1st North American Pika Conference. Teton Science Schools, Jackson Hole, WY. March 26, 2010.

Evolutionary Suicide and the Evolution of Angiogenesis in Cancer. Invited talk in the Physical Sciences Oncology Center at ASU Seminar series. Arizona State University. February 25, 2010.

The Evolutionary Ecology of Cancer. Plenary address in the VI International Seminar in Biomathematics (VI SEMBIOMAT). Lima, Peru. January 5, 2010.

Participant, Dynamics of Signal Transduction and of Gene Regulatory Networks. Workshop #2, Mathematical Biosciences Institute, Ohio State University. November 2-6, 2009.

Evolutionary Suicide in Cancer. Invited “chalk talk” to the Center for Biological Physics, Department of Physics, Arizona State University. September 29, 2009. (Invited by Robert Ros and Tim Newman.)

Participant, SMB 2009 Annual Meeting.  Society for Mathematical Biology, University of British Columbia, Vancouver B.C. July 27-30, 2009.

The Evolutionary Dynamics of ATP Allocation in Cancer: A Multiscale Model of Adenylate Dynamics in Angiogenic Tumors. Invited talk to the Faculty of Mathematics and Natural Sciences, University of Turku, Turku, Finland. May 27, 2009. (Invited by Dr. Kalle Parvinen.)

The Role of Stem Cells in the Evolution of Hypertumors in Malignant Neoplasia. In Stem Cells, Regeneration and Cancer Minisymposium. (Organized by R. Reshef, J. D. Nagy, E.Witten and A. Huysseune.) 2nd Euro Evo Devo Meeting, Ghent, Belgium. July 29-Aug. 1, 2008.

Natural Selection on Cell ATP Allocation May Constrain Evolutionary Suicide in Cancer: A Multiscale Model of Adenylate Dynamics in Vascularized Tumors. (Coauthor: Kelley Thompson.) Dynamical Systems in Biology and Medicine Minisymposium. (Organized by Yang Kuang, Bingtuan Li and Jiaxu Li.) 7th AIMS International Conference on Dynamical Systems, Differential Equations and Applications, Arlington, TX. May 18-21, 2008.

Production Systems in Biology: Stochastic Simulation of Complex Biological Networks.Marrakech International Conference and Workshop on Mathematical Biology, Marrakech, Morocco. January 3-8, 2008. (NOTE: Slightly more detailed than the presentation actually made at the conference.)

Evolutionary Suicide by Hypertumor: Can Cancer be Self-Defeating? Plenary address in the IV International Seminar in Biomathematics (IV SEMBIOMAT), Chiclayo, Peru. August 18, 2007.

Hypertumors in Malignant Neoplasia can be Caused by Tumor Phosphorus Demand. Modeling Cancer Growth and Treatment Minisymposium. (Organized by Thomas Hillen, University of Alberta and Dan Coombs, University of British Columbia.) 6th International Congress on Industrial and Applied Mathematics, Zurich, Switzerland. July 16-20, 2007.

Hypertumors in Malignant Neoplasia can be Caused by Tumor Phosphorus Demand. Tumor Modeling Minisymposium. (Organized by Thomas Hillen, University of Alberta and Dan Coombs, University of British Columbia.) CAIMS Annual Conference, Banff, Alberta, Canada. May 20-24, 2007.

Why Don’t All Whales Have Cancer? A Novel Hypothesis Resolving Peto’s paradox. Ecology and Evolution of Disease Dynamics Minisymposium. (Organized by Yang Kuang, James Elser, John Nagy, Timothy Newman & Val Smith). Society for Integrative and Comparative Biology Annual Meeting, Phoenix, AZ. January 3-7, 2007.

Biological stoichiometry of tumors: a test of the growth rate hypothesis using paired biopsy samples of human tumors. (Coauthors: Jim Elser, Marcia Kyle, Marilyn Smith, John Nagy. Presenter: Jim Elser.) Ecology and Evolution of Disease Dynamics Minisymposium. (Organized by Yang Kuang, James Elser, John Nagy, Timothy Newman & Val Smith.) Society for Integrative and Comparative Biology Annual Meeting, Phoenix, AZ. January 3-7, 2007.

Interdisciplinary training for undergraduates in biological and mathematical sciences at Arizona State University. (Coauthor: Yang Kuang.) Crossing Disciplinary Boundaries through Undergraduate Research Minisymposium (Organized by Amitabha Bose, NJIT), Joint SMB/SIAM Life Sciences Conference, Raleigh, N.C. August 2, 2006.

Evolutionary suicide by hypertumor: A novel hypothesis for the cause of necrosis in malignant neoplasia. Quantitative Study of Disease Minisymposium (Organized by Paul Tian, OSU), Joint SMB/SIAM Life Sciences Conference, Raleigh, N.C. July 31, 2006.

Modeling the effects of climate change on predator-prey cycles and population dynamics: A discussion. (Copresenters: Yang Kuang, Hao Wang and Irakli Loladze.) Workshop on Global Ecology, Mathematical Biosciences Institute, Ohio State University. June 2006.

Participant, American Association for Physical Anthropology Annual Meeting. Anchorage, AK. March 2006.

Participant, Workshop on Mathematical Models in Biology and Medicine. Arizona State University, Tempe, AZ. February 2006.

Undergraduate research in mathematical biology: a collaboration between ASU and SCC. Joint ECMTB/SMB meeting, Dresden, Germany. July 2005.

Integrating faculty development and outcomes assessment. (Co-presenter with Dr. John Neibling and Prof. Alan Jacobs.) 108th Annual Meeting of the Higher Learning Commission of the Commission of the North Central Association of Colleges and Schools.

Predicting effects of individual variation at population and community levels. (Co- and lead author: Paul Brunkow. Presented by Paul Brunkow.) Ecological Society of America Meeting, Spokane, Washington. 1999.

Adaptive dynamics of dispersal behavior in vertebrate metapopulations. Adaptive Dynamics Workshop, Matrahaza, Hungary. August 1996.

A model of evolutionarily attracting dispersal strategies in vertebrate metapopulations. International Conference on Systematics and Evolutionary Biology V, Budapest, Hungary. August 1996.

A structured metapopulation model and the evolution of dispersal strategies. Winter School on Population Dynamics, Woudschoten, The Netherlands. January 1996.

The evolutionary dynamics of dispersal behavior in vertebrate metapopulations. Fourth International Conference on Mathematical Population Dynamics. Rice University, Houston, Texas. May 1995.

A discrete-space structured metapopulation dynamics model (with Dr. Horst Thieme.) Fourth International Conference on Mathematical Population Dynamics. Rice University, Houston, Texas. May 1995.

The role of dispersal in population regulation of spruce grouse. CONFOR ‘89. Barrie, Ontario. February, 1989.

Dispersal and population regulation in spruce grouse. Northeast Natural Resources and Forestry Organization. Syracuse, New York. February 1988.

Posters

Co-infection dynamics in a novel model of the HIV/malaria syndemic. Coauthors and presenters: Nicholas Roberts, Aleesa Monaco. Coauthors: Ryan S. Maziarz, Michele V. Moreno, Chandler Grant, Clayton Grubb. Society for Mathematical Biology Annual Meeting. Salt Lake City, UT. July 19, 2017.

A novel mathematical model of HIV and malaria epidemiology. Coauthors and presenters: Clayton A. Grubb, Aleesa Monaco, Nicholas Roberts. Coauthors: Ryan Maziarz, Michele V. Moreno, Chandler Grant. Society for Mathematical Biology Annual Meeting. Salt Lake City, UT. July 19, 2017.

Artificial selection for dispersal in experimental metapopulations of confused flour beetles (Tribolium confusum). Coauthors and presenters: Adam T. Hrabovsky and Michele Moreno. Coauthors: Sarah Ung, Kerry Calhoun, Sean Hamilton. Society for Mathematical Biology Annual Meeting. Salt Lake City, UT. July 19, 2017.

Evolution of treatment resistance in advanced prostate cancer. Coauthors and presenters: Khoa Dang Ho, William Baker. Coauthors: Paige Mitchell, Jonathan Trautman, Chandler M. Grant, Alaina E. Daum. Society for Mathematical Biology Annual Meeting. Salt Lake City, UT. July 19, 2017.

Evolution of dispersal rates in an experimental metapopulation of confused flour beetles (Tribolium confusum). Coauthors and presenters: Perry Olliver, Kody Holmes, and Naomi Pier. 99th Ecological Society of America Annual Meeting (2014). Sacramento, CA. August 10-15, 2014.

A spatially explicit stochastic model of American pika (Ochotona princeps) metapopulation dynamics at Bodie, California. Coauthors and presenters: Andrew Nemecek, Easton R. White and Sky Arnett-Romero. 2013 Society for Mathematical Biology Annual Meeting. Tempe, AZ. June 10-13, 2013.

Testing the Growth Rate Hypothesis in cancer: Runaway selection in an ecological model of tumor growth. Coauthors and presenters: Daniel Stegman, David Ung and Kirsten Karr. Coauthor: Robert Alvarez. 2013 Society for Mathematical Biology Annual Meeting. Tempe, AZ. June 10-13, 2013.

Modeling an experimental metapopulation of confused flour beetles (Tribolium confusum). Coauthors and presenters: Perry Olliver,  Chalet N. Taylor, K. Harrison Holmes. Coauthors: Ryan Guthrie and Joshua Mark Bucur. 2013 Society for Mathematical Biology Annual Meeting. Tempe, AZ. June 10-13, 2013.

An investigation of behavioral patterns of the American pika at a new low-elevation study site. Coauthors and presenters: Easton R. White, Andrew Nemecek. 46th Joint Annual Meeting of the AZ/NM Chapters of the Wildlife and American Fisheries Society. Albuquerque, NM. February 7-9, 2013.

A new model of adenylate dynamics–adenylate catastrophe in physiologically depressed cells. Coauthors and presenters: Joseph D. Juliano, Stephanie Munson and Jacey Schnorr. Coauthor: Joel Wosely. International Conference on Industrial and Applied Mathematics 2011. Vancouver, B.C., Canada. July 18-22, 2011.

Assessing causation of annual population fluctuations in a predator-prey system using a series of discrete-time stochastic models. Coauthors and presenters: Easton R. White and Debra M. Groves. Coauthor: Joey S. Alsadi. International Conference on Industrial and Applied Mathematics 2011. Vancouver, B.C., Canada. July 18-22, 2011.