Molecular Genetics Lectures

Unit 1: Genes and Genomes Review

Quizzes for all lectures are available on the Canvas site. Log into Canvas.

Lecture Topic
1.1 Review of DNA biochemistry  |  Reading: Lecture 1.1 Notes
1.2 Review of gene expression.
1.3 Review of gene structure.
1.4 How do we discover DNA sequences?
1.5 How much do genomes vary?

Unit 2: DNA Replication and Recombination

Lecture Topic
2.1 Does genome size correlate with complexity?
2.2 Why do coding genes have introns?
2.3 How do gene families arise?
2.4 How do prokaryotes reproduce?
2.5 Eukaryotic cells are induced to divide via cell signaling.
2.6 Cell division in eukaryotes is regulated by multiple genes.
2.7 How do prokaryotes initiate DNA replication?

Unit 3: DNA Repair

Lecture Topic
3.1 Eukaryotic DNA replication requires a licensing factor.
3.2 DNA replication is performed by DNA polymerases.
3.3 A complex holoenzyme organizes DNA replication.
3.4 Cells can recognize and repair mismatched bases.
3.5 How do DNA repair systems make the correct repair?

Unit 4: Gene expression

Lecture Topic
4.1 How do bacteria initiate transcription?
4.2 How does transcription occur?
4.3 How is translation initiated?
4.4 How does translation occur?
4.5 Some gene regulation occurs at the level of transcription.
4.6 mRNA partially determines level of gene expression.
4.7 A variety of RNA molecules can regulate gene expression.