State what proportion of the human genome is the Alu insertion.
Calculate the allele frequencies from genetic data for single-gene, simple traits like the PV92,tPA25 and ACE-I Alu insertions.
State the 5 Hardy-Weinberg assumptions.
Calculate the expected genotype frequencies of a population in the next generation given current genotype frequencies assuming the population is in Hardy-Weinberg equilibrium.
State the Hardy-Weinberg theorem for the single gene, 2-allele case.
Explain why populations that fit the Hardy-Weinberg assumptions do not evolve, and why, therefore, evolution is expected to be very common.
State and explain all mechanisms of evolution, and relate them to violations of the Hardy-Weinberg assumptions.
Determine, using the Hardy-Weinberg theorem, if traits are evolving given genetic data from a population; be able to solve this problem using tPA25 and ACE-I data from northern Italy as examples.