Study Guide 2-8

Lecture 2.8 Competencies and Study Guide

Hardy-Weinberg

Vocabulary

  • SINE (Short interspersed element)
  • Transposable element
  • Allele frequency
  • Genotype frequency

Competencies

  1. Describe the Alu insertion in primate.
  2. State what proportion of the human genome is the Alu insertion.
  3. Calculate the allele frequencies from genetic data for single-gene, simple traits like the PV92, tPA25 and ACE-I Alu insertions.
  4. State the 5 Hardy-Weinberg assumptions.
  5. Calculate the expected genotype frequencies of a population in the next generation given current genotype frequencies assuming the population is in Hardy-Weinberg equilibrium.
  6. State the Hardy-Weinberg theorem for the single gene, 2-allele case.
  7. Explain why populations that fit the Hardy-Weinberg assumptions do not evolve, and why, therefore, evolution is expected to be very common.
  8. State and explain all mechanisms of evolution, and relate them to violations of the Hardy-Weinberg assumptions.
  9. Determine, using the Hardy-Weinberg theorem, if traits are evolving given genetic data from a population; be able to solve this problem using tPA25 and ACE-I data from northern Italy as examples.