Lecture 4.2 Competencies and Study Guide
Introduction to Metabolism
Vocabulary
- Entropy
- Free energy
- Enthalpy
- Endergoinc
- Exergonic
Competencies
- State the first and second laws of thermodynamics.
- Define work and energy.
- Describe potential and kinetic energy.
- Define entropy and Gibbs free energy.
- Explain the relationship between enthalpy, Gibbs free energy and entropy.
- Compare and contrast exergonic and endergonic reactions, including their ΔG and spontaneity.
- Describe the main endergonic and exergonic reactions involving ATP.
- State the ΔG of the ATP→ADP reaction.
- Explain why life and evolution do not violate the second law of thermodynamics.
- Explain, using the concept of coupled chemical reactions, how the amino acid glutamine is made even though its construction from glutamic acid and ammonia has a positive ΔG.